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MITOCHONDRIAL UNCOUPLING PROTEINS
Descriptors Found:
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DeCS
Descriptor
English
:
Mitochondrial Uncoupling Proteins
Descriptor
Spanish
:
Proteínas Desacopladoras Mitocondriales
Descriptor
Portuguese
:
Proteínas de Desacoplamento Mitocondrial
Synonyms
English
:
Mitochondrial UCPs
Uncoupling Proteins
UCPs, Mitochondrial
Uncoupling Proteins, Mitochondrial
Tree Number:
D12.776.157.530.937.598
D12.776.543.585.475.688
D12.776.543.585.937.696
D12.776.575.750.688
Definition
English
:
Mitochondrial anion
carrier proteins
that function as dimers and form proton channels in the INNER MITOCHONDRIAL MEMBRANE which creates proton leaks and uncouples
OXIDATIVE PHOSPHORYLATION
from ATP synthesis, resulting in the generation of heat instead of ATP.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56587
Unique Identifier:
D000071245
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS